Anzio is a city and comune on the coast of the Lazio region of Italy, about 56 km south of Rome.Well known for its seaside harbour setting, it is a fishing port and a departure point for ferries and hydroplanes to the Pontine Islands of Ponza, Palmarola and Ventotene. The city bears great historical significance as the site of Operation Shingle, a crucial Allied landing during World War II.