Travel from Palermo to Rome and discover this Lazio city of 2.300.000 inhabitants. The distance from Palermo to Rome is 683 kilometers; with Wanderio you can compare the available flights, trains, and buses to get from Palermo to Rome, so that you can organize your trip choosing the fastest route, the most comfortable or the cheapest one. You can choose among different choices and organize your trip according to your needs, depending on whether you are looking for the fastest, the most comfortable or perhaps the cheapest travel solution. For example, by choosing a flight from Palermo to Rome, you’ll get to your destination in about 1 hour on average; flight ticket prices start from 56 €. Going from Palermo to Rome by train instead? Prices for your ticket start from 19 € and the train journey takes about 10 hours on average.